Company

About Us

AbCheck discovers and optimizes human antibodies leveraging several proprietary platforms including in vitro/in vivo technologies. We use phage/yeast display libraries, mass humanization, antibody optimization and microfluidics to provide high-quality leads.

Flexibly adapting to our partners’ needs, we have proven our capabilities in multiple partnerships throughout the US and Europe.

OVERVIEW
  • Founded in 2009 as a spin-out of Affimed’s antibody technology discovery unit, headquartered in Plzeň, Czech Republic
  • Lean and agile team of experts with >20 years of expertise in antibody discovery and development
  • High-end technology boutique with ability to discover and develop antibodies against challenging targets and antibodies with therapeutically relevant biological functions
  • Projects tailored to a partner’s specific needs based on one of the industry's most versatile technology platforms
  • Service provider with variety of different business models and deal structures available
Mapa
Our Unique Approach

Meeting our partners’ needs in therapeutic antibody discovery and development

AbCheck offers a variety of services and technologies to meet the increased demand for high-quality antibody development candidates in today’s antibody discovery world.

Flexibly adapting to your needs, we offer customized solutions, developing novel approaches beyond antibody-antigen binding affinity criteria for the discovery of therapeutic antibodies with challenging Target Product Profiles.

Antibody Discovery - Tailor-made for a partner's Target Product Profiles

It’s our partner’s choice

  • Immunized repertoires or in vitro repertoires (Rabbit Mass Humanization)
  • Library- and Microfluidics-based approaches
  • With or without available soluble target protein
  • Screening in IgG or scFv format

IND-enabling in vitro studies

  • Cell-based assays (e.g. functional assays with primary immune cells (ADCC, ADCP, CDC, etc.), affinity studies, etc.)
  • ELISA and SPR-based assays (e.g. ADA ELISA, serum stability, affinity studies, etc.)
  • Assay development
  • IND-enabling study data reports for regulatory authorities

Challenges we can address

  • Epitope-specific targeting
  • Broad epitope coverage
  • Isoform-specific antibodies
  • Functional antibodies
  • Species cross-reactivity
  • Special stability requirements
  • Picomolar affinities
  • Sequence diversity

Our technologies for antibody characterization

  • ELISA, SPR, DSF
  • Flow cytometry, multimode readers for functional assays
WHO WE ARE

Our Management

Dr. Volker Lang
Managing
Director

Dr. Volker
Lang

Tomáš Jičínský
Managing Director
Finance and Administration

Tomáš
Jičínský

Dr. Oleh Petriv
Chief Technology
Officer

Dr. Oleh
Petriv

Dr. Claudia Wurzenberger
Vice President Project
Management

Dr. Claudia
Wurzenberger

Dr. Pavel Pitule
Vice President
Discovery

Dr. Pavel
Pitule

Dominik Hinz
Vice President
IND Assays

Dominik
Hinz

WHO WE ARE

Our Team

We are a highly skilled and experienced team operating transparently and in agreement with the highest ethical and corporate governance standards – mutual respect, integrity and trust are our foundation.

AbCheck fosters a close, collaborative working relationship with our clients. Our experience has demonstrated that this type of close interaction is very valuable in the development of successful projects. We insist on the highest quality standard, challenge conventional thinking within our team and cultivate rigorous problem solving, resulting in best solutions and scientific innovations that help to deliver optimal results in a timely fashion.

45+
Persons in 3 teams
100+
Coffees per day
Dr. Dattatrya
Shetti
Scientist New Technology
Development
Dr. Yuriy
Rzhepetskyy
Scientist Cell
Biologist
Dr. Ewa
Brzozowska
Project
Manager
Dr. Peter
Milovník
Director Molecular
Biology and Protein
Engineering
Dr. Joanna
Rybarczyk
Director Cell
Culture
Mohammad
Jamshidi
Engineer New Technology
Development
Dr. Michael
Tomaszowski
Director Bioassays
Dr. Josef
Čáslavský
Director Antibody
Characterization

Partnering

Discover our solutions
tailored to your needs!

Careers

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Our Services

Antibody
Discovery

Services

Antibody
Optimization

Services

Our Unique Platforms

Proprietary
Libraries

Technologies

Rabbit Mass
Humanization

Technologies

AbSieve®
Antibody
Selection

Technologies

AbAccel®
Antibody
Optimization

Technologies