The novel function-oriented discovery method is the fastest and most efficient way to isolate antibodies with therapeutically relevant biological functions
Starting with B cells of immunized rabbits or chickens, the method enables the de novo discovery of antibodies with agonistic properties, for example against GPCR targets.
Principle of
discovery
discovery
We create multi-transgenic sensor cell lines with your
GPCR targets
We immunize rabbits or chickens according to your preferences using proprietary strategies
We screen antibodies secreted by individual plasma cells using microfluidics-based functional assays in ultra-high throughput
AbCheck´s unique functional sorting technology allows the identification of extremely rare antibodies with specific biological functions
TECHNOLOGY DIAGRAM
Functional Sorting Principle
